Estudio epidemiológico de factores de riesgo asociados a refractura en mujeres con fractura vertebral osteoporótica durante 10 años de seguimiento / Epidemiological study of risk factors associated to refracture in women osteoporotic vertebral fracture during a 10-year follow-up

Objetivos. Los objetivos de este estudio son analizar las características epidemiológicas de las fracturas vertebrales osteoporóticas no quirúrgicas en mujeres, así como la posible relación que se da entre refractura y la existencia o no de tratamiento preventivo secundario contra la misma tras la primera fractura vertebral en un período de seguimiento de diez años. Métodos. Se realiza un estudio de cohortes clínicas retrospectivas de un total de 77 mujeres con fractura vertebral osteoporótica no quirúrgica con un tiempo de seguimiento de diez años. Como variable dependiente se considera el riesgo de refractura y como variables independientes la edad al ingreso, el número de fracturas vertebrales osteoporóticas, los cambios en la actividad de la vida, el dolor de espalda, el tratamiento, el tratamiento previo con corticoides, las benzodiacepinas o psicotrópicos, el tabaco, el consumo de alcohol, el déficit estrogénico, el peso, la vida sedentaria, el déficit visual, la patología tiroidea y la dificultad para levantarse de la silla. Resultados. El riesgo de nueva fractura vertebral o no vertebral a los 10 años tras la primera fractura es del 26%. Al comparar los riesgos de refractura atendiendo las características epidemiológicas, observamos que el porcentaje de refracturas aumenta con respecto al número de fracturas vertebrales en el primer episodio, siendo del 21,4% en el caso de una fractura vertebral, del 25,4% en el caso de dos fracturas vertebrales y del 50% cuando se trata de tres. La mayoría de las fracturas ocurren tras accidentes dentro de la rutina de la vida diaria. Sin embargo, no todos los pacientes experimentan un restablecimiento completo tras la fractura, ya que alrededor del 35% de estos enfermos sufren síntomas persistentes. Conclusiones. Los factores relacionados estadísticamente con la refractura son la edad mayor de 70 años, la deprivación de estrógenos y la dificultad para levantarse de la silla. Las pacientes que han recibido tratamiento frente a la osteoporosis tras la primera fractura vertebral tienen menos riesgo de refractura (odds ratio [OR]: 0,32) con respecto al grupo que no ha recibido tratamiento alguno frente a la osteoporosis(AU)

Objectives. This study has aimed to study the epidemiological characteristics of non-surgical osteoporotic vertebral fractures in women and the possible relationship existing between refracture and the existence or non-existence of secondary preventive treatment against it after the first vertebral fracture in a 10-year follow-up period. Methods. A clinical retrospective study of cohorts of a total of 77 women with non-surgical osteoporotic vertebral fracture with a 10-year follow-up period was performed. The dependent variable was considered to be risk of refracture and independent variables as age on admission, number of osteoporotic vertebral fractures, changes in life activity, back pain, treatment, previous treatment with corticosteroids, benzodiazepines or psychotropics, tobacco, alcohol consumption, estrogen deficit, weight, sedentary lifestyle, visual deficit, thyroid disease and difficulty getting up from the chair. Results. The risk of a new vertebral or non-vertebral fracture at 10 years after the first fracture is 26.0%. When the risks of refracture are compared according to the epidemiological characteristics, we observe that the percentage of refractures increases in regards to the number of vertebral fractures in the first episode, this being 21.4% in the case of one vertebral fracture, 25.4% in the case of two vertebral fractures and 50% when there are three vertebral fractures. Most of the fractures occur after accidents within the daily life routine. However, not all the patients have complete restablishment after the fracture, since approximately 35% of these patients suffer persistent symptoms. Conclusions. The factors that are statistically related with refracture are age over 70 years, estrogen deprivation and difficulty getting out of the chair. Patients who received treatment for osteoporosis after the first vertebral fracture have a lower risk of refracture (OR of 0.32) in regards to the group that did not receive any treatment for osteoporosis(AU)

Mid-term results in total hip arthroplasty with the basic noncemented hip prosthesis.

The Basic (IQL-Biomet, Valencia, Spain) hip prosthesis was used in 430 implant procedures, of which 417 had mean follow-up of 6 years. Radiographic follow-up was performed at 1, 3, 6, and 12 months postoperatively, and annually thereafter. The average Harris hip score improved from 35.7 preoperatively to 90.9 postoperatively. Clinical results after 2 years of follow-up showed 6% thigh pain, which decreased to 2% at 6 years. Radiographic evaluation demonstrated 22 cases of calcar resorption, 14% of which had distal pedestal formation. Heterotopic ossification was noted radiographically in 36%. These mid-term results obtained with the Basic prosthesis are similar to the findings of other series and warrant its use.

Transient osteoporosis of the hip.

We report four cases of transient hip osteoporosis studied between 1995 and 1997. All patients were men. The diagnosis was based on clinical symptoms, absence of abnormal laboratory tests, increased uptake in the femoral head and neck on Tc-99 bone scans and magnetic resonance imaging showing Oedema of the bone marrow. In three patients radiographs showed osteopenia of the head and neck of the involved femur, whereas no major radiographic changes were seen in the fourth patient. The clinical symptoms lasted 7 months and there was no recurrence after 8-24 months' follow-up.